Skip to main content
  • Nederlands
  • English

Internet search

Menu
  • What's new
    • News
    • Press releases
    • Calendar
  • About us
    • Who we are
    • Our building
    • Our history
  • Research
    • Publications
    • Research themes
    • Datasets
    • Facilities
    • Climate
  • Departments
    • Animal Ecology
    • Aquatic Ecology
    • Microbial Ecology
    • Terrestrial Ecology
    • Other
  • Themes
    • Chemical ecology
    • Disease ecology
    • Eco-evolutionary dynamics
    • Ecological epigenetics
    • Global environmental change
    • Microbiomes
    • Restoration ecology
  • Society
    • Relevance to society
    • Citizen science projects
    • Educational information
  • Vacancies
  • Contact
    • Address & route
    • Staff
Irene de Bruijn's picture

Dr. Irene de Bruijn

Researcher

Microbial Ecology


Research themes
  • Chemical ecology
  • Disease ecology
  • Eco-evolutionary dynamics
  • Microbiomes

  • Research expertise
  • Comparative genomics
  • Microbe-host interactions
  • Molecular microbiology

  • Page last updated: 26-08-2021

    I started studying Biology at the University of Utrecht because I wanted to study animal behaviour. But then I followed a course on molecular microbiology and I got intrigued by the communication among microorganisms and their interactions with their hosts. Microorganisms are of great importance in our daily life. Not only for us humans, but also in other animals and plants microorganims they influence our health, growth and development. 

    To date many studies describe which microbes are present (or absent) in different ecosystems, but how the microbial community influences its environment is largely lacking. My research focuses on the microbial community that suppresses plant and fish pathogens. By deciphering the interactions of bacterial consortia at a molecular and biochemical level an ecological understanding of the total microbial community will be pursued.

    For more information on current projects, see the website: https://nioo.knaw.nl/en/de-bruijn-group

     

    • CV
    • Groups
    • NIOO Projects
    • Other Projects
    • Key publications
    • Peer-reviewed publications
    • Popular-scientific publications
    • Ancillary positions

     

    2015-present NIOO-KNAW Junior research group leader on STW project: Deciphering the fish egg microbiome to mitigate diseases in aquaculture. 
    2011-2015 NIOO-KNAW Post-doc on STW project: Ecology and genomics of Lysobacter.
    2009-11

    University of Aberdeen, Scotland, UK

    Post-doc on BBSRC project: A systems biology based approach to functionally annotate and analyse the genome of the fish pathogenic oomycete Saprolegnia parasitica.
    2008-09 WUR

    Post-doc on NGI-Genomics project to identify antimicrobial compounds produced by Pseudomonas spp. against oomycetes and fungi. 

    2004-08 WUR PhD entitled: Cyclic lipopeptide biosynthesis and regulation in Pseudomonas fluorescens.
    1999-04 UU BSc and MSc Biology 

    OrcID: http://orcid.org/0000-0002-4889-3253

     

     

    Raaijmakers Group
    The overall goal of our research program is to unravel 1) mechanisms involved in the assembly of plant microbiomes. The functions of microbiomes we study in...Read more
    De Bruijn Group
    Read more
    Deciphering the microbiome of fish eggs to mitigate emerging diseases in aquaculture
    In aquaculture, diseases caused by the fungal-like oomycete Saprolegnia, but also ectoparasites are causing significant declines in fish and crayfish populations. To date, these diseases are controlled in aquaculture mainly by formalin treatment. However, the use of formalin will be banned in the...Read more

    ParaFish Control: Advanced tools and research strategies for parasite control in European farmed fish

     http://www.parafishcontrol.eu

    Risk factors for escalating saprolegniosis outbreaks in salmon farms (RIFE-SOS)

    http://gtr.rcuk.ac.uk/projects?ref=BB%2FP020224%2F1 

    ParaFish Control: Advanced tools and research strategies for parasite control in European farmed fish

     http://www.parafishcontrol.eu

    Risk factors for escalating saprolegniosis outbreaks in salmon farms (RIFE-SOS)

    http://gtr.rcuk.ac.uk/projects?ref=BB%2FP020224%2F1 

    For total list, see "Peer reviewed publications"

     

    De Bruijn, I., Liu, Y., Wiegertjes, G.F., Raaijmakers, J.M. 2017. Exploring fish microbial communities to mitigate emerging diseases in aquaculture. FEMS Microb Ecol. 94: fix161.

    Gómez Expósito, R., De Bruijn, I., Postma, J., Raaijmakers, J.M. 2017. Current Insights into the role of rhizosphere bacteria in disease suppressive soils. Front Microbiology 8: 2529.

    Medema, M.H., Kottmann, R. Yilmaz, P., Cummings, M., Biggins, J.B., Blin, K., De Bruijn, I., et al., 2015. The Minimum Information about a Biosynthetic Gene cluster (MIBiG) specification. NatChemBiol 11: 625–631.

    ^De Bruijn, I., ^Liu, Y.,  Jack, A.L.H., Van der Voort, M., Drynan, K., Skaar, I., Thoen, E., Van den Berg, H., Van West, P., Dieguez-Uribeondo, J., Sandoval-Sierra, J.V., Mendes, R. Mazzola, M., Raaijmakers, J.M. 2014. Deciphering the salmon egg microbiome to mitigate the emerging disease Saprolegniosis. ISME J 8: 2002-14.

    ^De Bruijn, I., ^Jiang, R.H.Y., ^Haas, B. J., Belmonte, R., Löbach, L., Christie, J., Van den Ackerveken, G., Bottin, A., Bulone, V., Díaz-Moreno, S.M., Dumas, B., Fan, L., Gaulin, E., Govers, F., Grenville-Briggs, L.J., Horner, N.R., Levin, J.Z., Mammella, M., Meijer, H.J.G., Morris, P., Nusbaum, C., Oome, S., Van Rooyen, D., Rzeszutek, E., Saraiva, M., Secombes, C.J., , M.F., Snel, B., Stassen, J.H.M., Sykes, S., Tripathy, S., Van den Berg, H., Vega-Arreguin, J.C., Wawra,, S., Young, S.K., Zeng, Q., Dieguez-Uribeondo, J., Russ, C., Tyler, B.M., Van West, P. 2013. Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica. PLOS Genetics 9: e1003272

    Mendes, R., Kruijt, M., De Bruijn, I., Dekkers, E., van der Voort, M., Schneider, J.H., Piceno, Y.M., DeSantis, T.Z., Andersen, G.L., Bakker, P.A., Raaijmakers, J.M. 2011. Deciphering the rhizosphere microbiome for disease-suppressive bacteria. Science 332: 1097-100.

    ^De Bruijn, I.,^Raaijmakers, J. M., ^Nybroe, O., and ^Ongena, M. 2010. Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics. FEMS Microbiology Reviews 34: 1037-62

    De Bruijn, I., and Raaijmakers, J.M. 2009. Regulation of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens by the ClpP protease. J Bacteriol 191:1910-23. 

    Walker, L.A., Munro, C.A., De Bruijn, I., Lenardon, M.D., McKinnon, A., and Gow, N.A. 2008. Stimulation of chitin synthesis rescues Candida albicans from echinocandins. PLOS Pathog 4(4):e1000040.

    De Bruijn, I., de Kock, M.J., Yang, M., de Waard, P., van Beek, T.A., and Raaijmakers, J.M. 2007. Genome-based discovery, structure prediction and functional analysis of cyclic lipopeptide antibiotics in Pseudomonas species. Mol Microbiol 63:417-28. 

    Contact

    +31 (0)317 473 400

    Droevendaalsesteeg 10
    6708 PB Wageningen 
    +31 (0)317 47 34 00

    Postbus 50 
    6700 AB Wageningen

    I.deBruijn@nioo.knaw.nl

    Contact Form

    • KNAW
    • intranet
    • privacy statement
    • login

    NIOO KNAW